Ivermectin has become so popular that livestock supply stores are running out of the horse parasite therapy.  The medication has very limited use for a variety of uncommon worm infections in humans; however, think of the difference in size of a horse compared to a human, so a usual dose for a horse is an overdose for a human.  It also could contain ingredients intended only for animals.  Some doctors who gave Ivermectin to infected COVID patients saw seemingly positive effects. However, more studies show it has little to no effect when it comes to treat COVID-19.

In recent weeks there has been a dramatic increase in calls to poison centers by people who are taking ivermectin intended for animals as a dewormer. ERs are seeing more patients who have overdosed on the horse dewormer.  Joe Rogan a famous podcaster and unfortunately also an anti-vaxer “threw the kitchen sink including ivermectin” at himself when he tested positive for COVID.

Side effects vary depending on whether it’s taken by mouth or topically for certain skin infections.  Oral tablets can cause drowsiness, nausea, dizziness, vomiting, diarrhea, low blood pressure and rarely an increase in heart rate and seizures.  Coma and even death has occurred. The topical version can cause skin rash while dry skin and stinging pain are severe but rare.   In doses appropriate for humans can interact with other medications like blood thinners.

The CDC and the National Institute for Health has warned that ivermectin has not been proven as a way to prevent or treat COVID 19 as has the National Institute for Health.  The pharmaceutical company Merck that manufactures the med has recommended not using it for COVID of any severity. Results from well-designed well-conducted clinical trials are needed to provide more specific evidence-based guidance on the role of ivermectin.  There is some initial research underway.

Given the rising number of COVID deaths, it’s not surprising that some may be looking at unconventional treatments for COVID that have not been approved or authorized.

Peace,

Irwin J. Kash MD